Developing and Transferring Remote Swab TOC Method

Developing and Transferring Remote Swab TOC Method

03/21/2017, 10:30 AM - 11:15 AM

Meeting Room 1


A cleaning program is designed to provide assurance that process related residues and cleaning agents are reduced to an acceptable level after cleaning. During cleaning validation surfaces are often sampled directly using Total Organic Carbon (TOC) swabbing to evaluate residual contaminants remaining on the process equipment. Method development is typically conducted to determine total TOC product recovery performed under controlled laboratory conditions using known product concentration within a given surface area. However, swabbing of commercial equipment may require confined space entry (CSE), which poses significant safety concerns and increases potential for contaminating intended swab sites. This paper explores remote swabbing techniques and critical parameters that can eliminate possible safety challengers, reducing the potential for contaminating swab sites, while obtaining adequate recovery results.


  • Kate Boswell


    Lab Study Analyst I

    Hyde Engineering + Consulting

  • Clare Hogan


    Marketing Coordinator

    Hyde Engineering + Consulting

Type of Session

  1. Type of Session

Learning Objectives

  1. Learning Objectives 1. Advantages of remote swab over swabbing through confined space entry. 2. How to develop a remote swab method. 3. Appropriate criteria for the qualification of a remote swab method and the technicians executing it.


  1. Track
    Enhancing Processing & Production Utilizing Innovation

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