Processes and factory of the future. Single use and flexible for faster, cheaper and safer manufacturing

Processes and factory of the future. Single use and flexible for faster, cheaper and safer manufacturing

03/21/2017, 10:30 AM - 11:15 AM

Meeting Room 2

Language:
English

Despite the introduction of new technologies, the majority of Biotech processes and facilities still contain a number of stainless steel and multi-use equipment. We have made the decision to move away from this traditional setup and implement full Single-Use processes at Laboratory and manufacturing scale. This change from Multi-use to Single-use was developed in parallel with the facility revamping and a global strategic development of flexible facilities concepts. We have developed an integrated USP & DSP that offers significant practical and economic advantages without sacrificing performance and robustness. This new holistic process can be run in either batch or continuous mode of operation. This single use leverages existing technologies with the potential to "change the game". The integration of a new train at 2,000L scale in a flexible factory is presented as well as future development in flexible factories modular-based.

Contributors

  • Christian Cattaruzza

    Speaker

    Marketing Director - Process Solutions

    MilliporeSigma

  • Sebastien Ribault

    Speaker

    Director Biodevelopment/ End to End Delivery

    MilliporeSigma

    Sébastien Ribault is Director BioDevelopment and End to End delivery. He leads activities going from Cell Line Generation to Biotech Facility design...

Type of Session

  1. Type of Session
    Session

Learning Objectives

  1. Learning Objectives 1. We will learn global market trends in Biopharmaceutical industry: risks and opportunities as well as where the industry expects to build production capacity. Understand the challenge which consist in investing quickly to be the first to enter the market while lowering project financial risks and ensuring drug products COGS are competitive and affordable locally. 2. We will see how a clever implementation of single use technologies across USP/DSP process of a Mab can impact process efficiency and flexibility through concrete examples of comparing SST with SU processes. 3. We will discuss the challenges faced in designing and constructing a production facility that can produce different Mabs from clinical studies through commercial production. We will look forward 10 to 15 years and consider different production scales utilizing single use equipment in conjunction with flexible facility design, and potential economic impacts.

Categories

  1. Track
    Implementing Modularity and Speed in Facilities/Facilities Management

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